DNA methylome analysis identifies accelerated epigenetic ageing associated with postmenopausal breast cancer susceptibility.
Identifieur interne : 000E79 ( Main/Exploration ); précédent : 000E78; suivant : 000E80DNA methylome analysis identifies accelerated epigenetic ageing associated with postmenopausal breast cancer susceptibility.
Auteurs : Srikant Ambatipudi [France] ; Steve Horvath [États-Unis] ; Flavie Perrier [France] ; Cyrille Cuenin [France] ; Hector Hernandez-Vargas [France] ; Florence Le Calvez-Kelm [France] ; Geoffroy Durand [France] ; Graham Byrnes [France] ; Pietro Ferrari [France] ; Liacine Bouaoun [France] ; Athena Sklias [France] ; Véronique Chajes [France] ; Kim Overvad [Danemark] ; Gianluca Severi [Australie] ; Laura Baglietto [Australie] ; Françoise Clavel-Chapelon [France] ; Rudolf Kaaks [Allemagne] ; Myrto Barrdahl [Allemagne] ; Heiner Boeing [Allemagne] ; Antonia Trichopoulou [Grèce] ; Pagona Lagiou [États-Unis] ; Androniki Naska [Grèce] ; Giovanna Masala [Italie] ; Claudia Agnoli [Italie] ; Silvia Polidoro [Italie] ; Rosario Tumino [Italie] ; Salvatore Panico [Italie] ; Martijn Dollé [Pays-Bas] ; Petra H M. Peeters [Royaume-Uni] ; N Charlotte Onland-Moret [Pays-Bas] ; Torkjel M. Sandanger [Norvège] ; Therese H. N St [Norvège] ; Elisabete Weiderpass [Finlande] ; J Ram N Quir S [Espagne] ; Antonio Agudo [Espagne] ; Miguel Rodriguez-Barranco [Espagne] ; José María Huerta Casta O [Espagne] ; Aurelio Barricarte [Espagne] ; Ander Matheu Fernández [Espagne] ; Ruth C. Travis [Royaume-Uni] ; Paolo Vineis [Royaume-Uni] ; David C. Muller [Royaume-Uni] ; Elio Riboli [Royaume-Uni] ; Marc Gunter [France] ; Isabelle Romieu [France] ; Zdenko Herceg [France]Source :
- European journal of cancer (Oxford, England : 1990) [ 1879-0852 ] ; 2017.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Facteurs de l'âge, Femelle, Humains, Méthylation de l'ADN (génétique), Méthylation de l'ADN (physiologie), Post-ménopause (génétique), Prédisposition génétique à une maladie (génétique), Sujet âgé, Tumeurs du sein (génétique), Épigenèse génétique (génétique), Épigénomique, Études cas-témoins.
- MESH :
English descriptors
- KwdEn :
- MESH :
- genetics : Breast Neoplasms, DNA Methylation, Epigenesis, Genetic, Genetic Predisposition to Disease, Postmenopause.
- physiology : DNA Methylation.
- Adult, Age Factors, Aged, Case-Control Studies, Epigenomics, Female, Humans, Middle Aged.
Abstract
A vast majority of human malignancies are associated with ageing, and age is a strong predictor of cancer risk. Recently, DNA methylation-based marker of ageing, known as 'epigenetic clock', has been linked with cancer risk factors. This study aimed to evaluate whether the epigenetic clock is associated with breast cancer risk susceptibility and to identify potential epigenetics-based biomarkers for risk stratification.
DOI: 10.1016/j.ejca.2017.01.014
PubMed: 28259012
Affiliations:
- Allemagne, Australie, Danemark, Espagne, Finlande, France, Grèce, Italie, Norvège, Pays-Bas, Royaume-Uni, États-Unis
- Angleterre, Attique (région), Auvergne-Rhône-Alpes, Bade-Wurtemberg, Californie, Catalogne, District de Karlsruhe, Grand Londres, Massachusetts, Oxfordshire, Piémont, Rhône-Alpes, Utrecht (province)
- Athènes, Barcelone, Boston, Heidelberg, Londres, Lyon, Oxford, Turin, Utrecht
- Université d'Oxford
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Le document en format XML
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Research on Cancer (IARC), Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer (IARC), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Byrnes, Graham" sort="Byrnes, Graham" uniqKey="Byrnes G" first="Graham" last="Byrnes">Graham Byrnes</name><affiliation wicri:level="3"><nlm:affiliation>International Agency for Research on Cancer (IARC), Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer (IARC), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Ferrari, Pietro" sort="Ferrari, Pietro" uniqKey="Ferrari P" first="Pietro" last="Ferrari">Pietro Ferrari</name><affiliation wicri:level="3"><nlm:affiliation>International Agency for Research on Cancer (IARC), Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer (IARC), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Bouaoun, Liacine" sort="Bouaoun, Liacine" uniqKey="Bouaoun L" first="Liacine" last="Bouaoun">Liacine Bouaoun</name><affiliation wicri:level="3"><nlm:affiliation>International Agency for Research on Cancer (IARC), Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer (IARC), Lyon</wicri:regionArea><placeName><region 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France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer (IARC), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Overvad, Kim" sort="Overvad, Kim" uniqKey="Overvad K" first="Kim" last="Overvad">Kim Overvad</name><affiliation wicri:level="1"><nlm:affiliation>Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus</wicri:regionArea><wicri:noRegion>Aarhus</wicri:noRegion></affiliation></author><author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name><affiliation wicri:level="1"><nlm:affiliation>Inserm, Centre de Recherche en Epidémiologie et Santé des Populations (CESP, U1018), Université Paris-Saclay, Université Paris-Sud, UVSQ, Institut Gustave Roussy, Villejuif, France; Human Genetics Foundation (HuGeF), Torino, Italy; Cancer Epidemiology Centre, Cancer Council Victoria and Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourn, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Inserm, Centre de Recherche en Epidémiologie et Santé des Populations (CESP, U1018), Université Paris-Saclay, Université Paris-Sud, UVSQ, Institut Gustave Roussy, Villejuif, France; Human Genetics Foundation (HuGeF), Torino, Italy; Cancer Epidemiology Centre, Cancer Council Victoria and Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourn</wicri:regionArea><wicri:noRegion>University of Melbourn</wicri:noRegion></affiliation></author><author><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name><affiliation wicri:level="1"><nlm:affiliation>Inserm, Centre de Recherche en Epidémiologie et Santé des Populations (CESP, U1018), Université Paris-Saclay, Université Paris-Sud, UVSQ, Institut Gustave Roussy, Villejuif, France; Cancer Epidemiology Centre, Cancer Council Victoria and Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourn, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Inserm, Centre de Recherche en Epidémiologie et Santé des Populations (CESP, U1018), Université Paris-Saclay, Université Paris-Sud, UVSQ, Institut Gustave Roussy, Villejuif, France; Cancer Epidemiology Centre, Cancer Council Victoria and Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourn</wicri:regionArea><wicri:noRegion>University of Melbourn</wicri:noRegion></affiliation></author><author><name sortKey="Clavel Chapelon, Francoise" sort="Clavel Chapelon, Francoise" uniqKey="Clavel Chapelon F" first="Françoise" last="Clavel-Chapelon">Françoise Clavel-Chapelon</name><affiliation wicri:level="1"><nlm:affiliation>Inserm, Centre de Recherche en Epidémiologie et Santé des Populations (CESP, U1018), Université Paris-Saclay, Université Paris-Sud, UVSQ, Institut Gustave Roussy, Villejuif, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Inserm, Centre de Recherche en Epidémiologie et Santé des Populations (CESP, U1018), Université Paris-Saclay, Université Paris-Sud, UVSQ, Institut Gustave Roussy, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Kaaks, Rudolf" sort="Kaaks, Rudolf" uniqKey="Kaaks R" first="Rudolf" last="Kaaks">Rudolf Kaaks</name><affiliation wicri:level="3"><nlm:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Barrdahl, Myrto" sort="Barrdahl, Myrto" uniqKey="Barrdahl M" first="Myrto" last="Barrdahl">Myrto Barrdahl</name><affiliation wicri:level="3"><nlm:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Boeing, Heiner" sort="Boeing, Heiner" uniqKey="Boeing H" first="Heiner" last="Boeing">Heiner Boeing</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal</wicri:regionArea><wicri:noRegion>Nuthetal</wicri:noRegion><wicri:noRegion>Nuthetal</wicri:noRegion><wicri:noRegion>Nuthetal</wicri:noRegion></affiliation></author><author><name sortKey="Trichopoulou, Antonia" sort="Trichopoulou, Antonia" uniqKey="Trichopoulou A" first="Antonia" last="Trichopoulou">Antonia Trichopoulou</name><affiliation wicri:level="3"><nlm:affiliation>Hellenic Health Foundation, Athens, Greece; WHO Collaborating Center for Nutrition and Health, Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Athens, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Hellenic Health Foundation, Athens, Greece; WHO Collaborating Center for Nutrition and Health, Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Athens</wicri:regionArea><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Lagiou, Pagona" sort="Lagiou, Pagona" uniqKey="Lagiou P" first="Pagona" last="Lagiou">Pagona Lagiou</name><affiliation wicri:level="3"><nlm:affiliation>Hellenic Health Foundation, Athens, Greece; WHO Collaborating Center for Nutrition and Health, Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Athens, Greece; Department of Epidemiology, Harvard School of Public Health, Boston, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Hellenic Health Foundation, Athens, Greece; WHO Collaborating Center for Nutrition and Health, Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Athens, Greece; Department of Epidemiology, Harvard School of Public Health, Boston</wicri:regionArea><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Naska, Androniki" sort="Naska, Androniki" uniqKey="Naska A" first="Androniki" last="Naska">Androniki Naska</name><affiliation wicri:level="3"><nlm:affiliation>Hellenic Health Foundation, Athens, Greece; WHO Collaborating Center for Nutrition and Health, Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Athens, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Hellenic Health Foundation, Athens, Greece; WHO Collaborating Center for Nutrition and Health, Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Athens</wicri:regionArea><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Masala, Giovanna" sort="Masala, Giovanna" uniqKey="Masala G" first="Giovanna" last="Masala">Giovanna Masala</name><affiliation wicri:level="1"><nlm:affiliation>Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute - ISPO, Florence, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute - ISPO, Florence</wicri:regionArea><wicri:noRegion>Florence</wicri:noRegion></affiliation></author><author><name sortKey="Agnoli, Claudia" sort="Agnoli, Claudia" uniqKey="Agnoli C" first="Claudia" last="Agnoli">Claudia Agnoli</name><affiliation wicri:level="1"><nlm:affiliation>Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milano, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milano</wicri:regionArea><wicri:noRegion>Milano</wicri:noRegion></affiliation></author><author><name sortKey="Polidoro, Silvia" sort="Polidoro, Silvia" uniqKey="Polidoro S" first="Silvia" last="Polidoro">Silvia Polidoro</name><affiliation wicri:level="3"><nlm:affiliation>Human Genetics Foundation (HuGeF), Torino, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Human Genetics Foundation (HuGeF), Torino</wicri:regionArea><placeName><settlement type="city">Turin</settlement><region type="région" nuts="2">Piémont</region></placeName></affiliation></author><author><name sortKey="Tumino, Rosario" sort="Tumino, Rosario" uniqKey="Tumino R" first="Rosario" last="Tumino">Rosario Tumino</name><affiliation wicri:level="1"><nlm:affiliation>Cancer Registry and Histopathology Unit, "Civic M.P. Arezzo" Hospital, ASP Ragusa, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Cancer Registry and Histopathology Unit, "Civic M.P. Arezzo" Hospital, ASP Ragusa</wicri:regionArea><wicri:noRegion>ASP Ragusa</wicri:noRegion></affiliation></author><author><name sortKey="Panico, Salvatore" sort="Panico, Salvatore" uniqKey="Panico S" first="Salvatore" last="Panico">Salvatore Panico</name><affiliation wicri:level="1"><nlm:affiliation>Dipartimento di Medicina Clinica e Chirurgia, Federico II University, Naples, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Medicina Clinica e Chirurgia, Federico II University, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Dolle, Martijn" sort="Dolle, Martijn" uniqKey="Dolle M" first="Martijn" last="Dollé">Martijn Dollé</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven</wicri:regionArea><wicri:noRegion>Bilthoven</wicri:noRegion></affiliation></author><author><name sortKey="Peeters, Petra H M" sort="Peeters, Petra H M" uniqKey="Peeters P" first="Petra H M" last="Peeters">Petra H M. Peeters</name><affiliation wicri:level="3"><nlm:affiliation>Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands; MRC-PHE Centre for Environment and Health, Dept of Epidemiology and Biostatistics, School of Public Health, Imperial College, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands; MRC-PHE Centre for Environment and Health, Dept of Epidemiology and Biostatistics, School of Public Health, Imperial College, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Onland Moret, N Charlotte" sort="Onland Moret, N Charlotte" uniqKey="Onland Moret N" first="N Charlotte" last="Onland-Moret">N Charlotte Onland-Moret</name><affiliation wicri:level="3"><nlm:affiliation>Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Sandanger, Torkjel M" sort="Sandanger, Torkjel M" uniqKey="Sandanger T" first="Torkjel M" last="Sandanger">Torkjel M. Sandanger</name><affiliation wicri:level="1"><nlm:affiliation>Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø</wicri:regionArea><wicri:noRegion>Tromsø</wicri:noRegion></affiliation></author><author><name sortKey="N St, Therese H" sort="N St, Therese H" uniqKey="N St T" first="Therese H" last="N St">Therese H. N St</name><affiliation wicri:level="1"><nlm:affiliation>Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø</wicri:regionArea><wicri:noRegion>Tromsø</wicri:noRegion></affiliation></author><author><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name><affiliation wicri:level="1"><nlm:affiliation>Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway; Department of Research, Cancer Registry of Norway, Institute of Population-Based Cancer Research, Oslo, Norway; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Genetic Epidemiology Group, Folkhälsan Research Center, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway; Department of Research, Cancer Registry of Norway, Institute of Population-Based Cancer Research, Oslo, Norway; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Genetic Epidemiology Group, Folkhälsan Research Center, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Quir S, J Ram N" sort="Quir S, J Ram N" uniqKey="Quir S J" first="J Ram N" last="Quir S">J Ram N Quir S</name><affiliation wicri:level="1"><nlm:affiliation>Public Health Directorate, Asturias, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Public Health Directorate, Asturias</wicri:regionArea><wicri:noRegion>Asturias</wicri:noRegion></affiliation></author><author><name sortKey="Agudo, Antonio" sort="Agudo, Antonio" uniqKey="Agudo A" first="Antonio" last="Agudo">Antonio Agudo</name><affiliation wicri:level="3"><nlm:affiliation>Unit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology-IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Unit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology-IDIBELL, L'Hospitalet de Llobregat, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Rodriguez Barranco, Miguel" sort="Rodriguez Barranco, Miguel" uniqKey="Rodriguez Barranco M" first="Miguel" last="Rodriguez-Barranco">Miguel Rodriguez-Barranco</name><affiliation wicri:level="1"><nlm:affiliation>Escuela Andaluza de Salud Pública, Instituto de Investigación Biosanitaria ibsn Granada, Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain; CIBER de Epidemiología y Salud Pública (CIBERESP), Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Escuela Andaluza de Salud Pública, Instituto de Investigación Biosanitaria ibsn Granada, Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain; CIBER de Epidemiología y Salud Pública (CIBERESP)</wicri:regionArea><wicri:noRegion>Spain; CIBER de Epidemiología y Salud Pública (CIBERESP)</wicri:noRegion></affiliation></author><author><name sortKey="Huerta Casta O, Jose Maria" sort="Huerta Casta O, Jose Maria" uniqKey="Huerta Casta O J" first="José María" last="Huerta Casta O">José María Huerta Casta O</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Murcia Regional Health Council, IMIB-Arrixaca, Murcia, Spain; CIBER de Epidemiología y Salud Pública (CIBERESP), Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Epidemiology, Murcia Regional Health Council, IMIB-Arrixaca, Murcia, Spain; CIBER de Epidemiología y Salud Pública (CIBERESP)</wicri:regionArea><wicri:noRegion>Spain; CIBER de Epidemiología y Salud Pública (CIBERESP)</wicri:noRegion></affiliation></author><author><name sortKey="Barricarte, Aurelio" sort="Barricarte, Aurelio" uniqKey="Barricarte A" first="Aurelio" last="Barricarte">Aurelio Barricarte</name><affiliation wicri:level="1"><nlm:affiliation>Navarra Public Health Institute, Pamplona, Spain; Navarra Institute for Health Research (IdiSNA) Pamplona, Spain; CIBER de Epidemiología y Salud Pública (CIBERESP), Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Navarra Public Health Institute, Pamplona, Spain; Navarra Institute for Health Research (IdiSNA) Pamplona, Spain; CIBER de Epidemiología y Salud Pública (CIBERESP)</wicri:regionArea><wicri:noRegion>Spain; CIBER de Epidemiología y Salud Pública (CIBERESP)</wicri:noRegion></affiliation></author><author><name sortKey="Fernandez, Ander Matheu" sort="Fernandez, Ander Matheu" uniqKey="Fernandez A" first="Ander Matheu" last="Fernández">Ander Matheu Fernández</name><affiliation wicri:level="1"><nlm:affiliation>Cellular Oncology Group, Biodonostia Health Research Institute, Paseo Dr. Beguiristain s/n, San Sebastian, Spain; IKERBASQUE, Basque Foundation, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Cellular Oncology Group, Biodonostia Health Research Institute, Paseo Dr. Beguiristain s/n, San Sebastian, Spain; IKERBASQUE, Basque Foundation</wicri:regionArea><wicri:noRegion>Basque Foundation</wicri:noRegion></affiliation></author><author><name sortKey="Travis, Ruth C" sort="Travis, Ruth C" uniqKey="Travis R" first="Ruth C" last="Travis">Ruth C. Travis</name><affiliation wicri:level="4"><nlm:affiliation>Cancer Epidemiology Unit, Nuffield Department of Population Health University of Oxford, Oxford UK.</nlm:affiliation><orgName type="university">Université d'Oxford</orgName><country>Royaume-Uni</country><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Vineis, Paolo" sort="Vineis, Paolo" uniqKey="Vineis P" first="Paolo" last="Vineis">Paolo Vineis</name><affiliation wicri:level="3"><nlm:affiliation>School of Public Health, Imperial College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Public Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Muller, David C" sort="Muller, David C" uniqKey="Muller D" first="David C" last="Muller">David C. Muller</name><affiliation wicri:level="3"><nlm:affiliation>School of Public Health, Imperial College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Public Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name><affiliation wicri:level="3"><nlm:affiliation>School of Public Health, Imperial College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Public Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Gunter, Marc" sort="Gunter, Marc" uniqKey="Gunter M" first="Marc" last="Gunter">Marc Gunter</name><affiliation wicri:level="3"><nlm:affiliation>International Agency for Research on Cancer (IARC), Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer (IARC), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Romieu, Isabelle" sort="Romieu, Isabelle" uniqKey="Romieu I" first="Isabelle" last="Romieu">Isabelle Romieu</name><affiliation wicri:level="3"><nlm:affiliation>International Agency for Research on Cancer (IARC), Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer (IARC), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Herceg, Zdenko" sort="Herceg, Zdenko" uniqKey="Herceg Z" first="Zdenko" last="Herceg">Zdenko Herceg</name><affiliation wicri:level="3"><nlm:affiliation>International Agency for Research on Cancer (IARC), Lyon, France. Electronic address: herceg@iarc.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer (IARC), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28259012</idno><idno type="pmid">28259012</idno><idno type="doi">10.1016/j.ejca.2017.01.014</idno><idno type="wicri:Area/PubMed/Corpus">000D82</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000D82</idno><idno type="wicri:Area/PubMed/Curation">000D79</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000D79</idno><idno type="wicri:Area/PubMed/Checkpoint">000D79</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000D79</idno><idno type="wicri:Area/Ncbi/Merge">004412</idno><idno type="wicri:Area/Ncbi/Curation">004412</idno><idno type="wicri:Area/Ncbi/Checkpoint">004412</idno><idno type="wicri:Area/Main/Merge">000E74</idno><idno type="wicri:Area/Main/Curation">000E79</idno><idno type="wicri:Area/Main/Exploration">000E79</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">DNA methylome analysis identifies accelerated epigenetic ageing associated with postmenopausal breast cancer susceptibility.</title><author><name sortKey="Ambatipudi, Srikant" sort="Ambatipudi, Srikant" uniqKey="Ambatipudi S" first="Srikant" last="Ambatipudi">Srikant Ambatipudi</name><affiliation wicri:level="3"><nlm:affiliation>International Agency for Research on Cancer (IARC), Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer (IARC), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Horvath, Steve" sort="Horvath, Steve" uniqKey="Horvath S" first="Steve" last="Horvath">Steve Horvath</name><affiliation wicri:level="2"><nlm:affiliation>Human Genetics and Biostatistics, University of California Los Angeles, Los Angeles, CA 90095-7088, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genetics and Biostatistics, University of California Los Angeles, Los Angeles, CA 90095-7088</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Perrier, Flavie" sort="Perrier, Flavie" uniqKey="Perrier F" first="Flavie" last="Perrier">Flavie Perrier</name><affiliation wicri:level="3"><nlm:affiliation>International Agency for Research on Cancer (IARC), Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer (IARC), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Cuenin, Cyrille" sort="Cuenin, Cyrille" uniqKey="Cuenin C" first="Cyrille" last="Cuenin">Cyrille Cuenin</name><affiliation wicri:level="3"><nlm:affiliation>International Agency for Research on Cancer (IARC), Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer (IARC), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Hernandez Vargas, Hector" sort="Hernandez Vargas, Hector" uniqKey="Hernandez Vargas H" first="Hector" last="Hernandez-Vargas">Hector Hernandez-Vargas</name><affiliation wicri:level="3"><nlm:affiliation>International Agency for Research on Cancer (IARC), Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer (IARC), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Le Calvez Kelm, Florence" sort="Le Calvez Kelm, Florence" uniqKey="Le Calvez Kelm F" first="Florence" last="Le Calvez-Kelm">Florence Le Calvez-Kelm</name><affiliation wicri:level="3"><nlm:affiliation>International Agency for Research on Cancer (IARC), Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer (IARC), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Durand, Geoffroy" sort="Durand, Geoffroy" uniqKey="Durand G" first="Geoffroy" last="Durand">Geoffroy Durand</name><affiliation wicri:level="3"><nlm:affiliation>International Agency for Research on Cancer (IARC), Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer (IARC), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Byrnes, Graham" sort="Byrnes, Graham" uniqKey="Byrnes G" first="Graham" last="Byrnes">Graham Byrnes</name><affiliation wicri:level="3"><nlm:affiliation>International Agency for Research on Cancer (IARC), Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer (IARC), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Ferrari, Pietro" sort="Ferrari, Pietro" uniqKey="Ferrari P" first="Pietro" last="Ferrari">Pietro Ferrari</name><affiliation wicri:level="3"><nlm:affiliation>International Agency for Research on Cancer (IARC), Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer (IARC), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Bouaoun, Liacine" sort="Bouaoun, Liacine" uniqKey="Bouaoun L" first="Liacine" last="Bouaoun">Liacine Bouaoun</name><affiliation wicri:level="3"><nlm:affiliation>International Agency for Research on Cancer (IARC), Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer (IARC), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Sklias, Athena" sort="Sklias, Athena" uniqKey="Sklias A" first="Athena" last="Sklias">Athena Sklias</name><affiliation wicri:level="3"><nlm:affiliation>International Agency for Research on Cancer (IARC), Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer (IARC), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Chajes, Veronique" sort="Chajes, Veronique" uniqKey="Chajes V" first="Véronique" last="Chajes">Véronique Chajes</name><affiliation wicri:level="3"><nlm:affiliation>International Agency for Research on Cancer (IARC), Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer (IARC), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Overvad, Kim" sort="Overvad, Kim" uniqKey="Overvad K" first="Kim" last="Overvad">Kim Overvad</name><affiliation wicri:level="1"><nlm:affiliation>Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus</wicri:regionArea><wicri:noRegion>Aarhus</wicri:noRegion></affiliation></author><author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name><affiliation wicri:level="1"><nlm:affiliation>Inserm, Centre de Recherche en Epidémiologie et Santé des Populations (CESP, U1018), Université Paris-Saclay, Université Paris-Sud, UVSQ, Institut Gustave Roussy, Villejuif, France; Human Genetics Foundation (HuGeF), Torino, Italy; Cancer Epidemiology Centre, Cancer Council Victoria and Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourn, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Inserm, Centre de Recherche en Epidémiologie et Santé des Populations (CESP, U1018), Université Paris-Saclay, Université Paris-Sud, UVSQ, Institut Gustave Roussy, Villejuif, France; Human Genetics Foundation (HuGeF), Torino, Italy; Cancer Epidemiology Centre, Cancer Council Victoria and Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourn</wicri:regionArea><wicri:noRegion>University of Melbourn</wicri:noRegion></affiliation></author><author><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name><affiliation wicri:level="1"><nlm:affiliation>Inserm, Centre de Recherche en Epidémiologie et Santé des Populations (CESP, U1018), Université Paris-Saclay, Université Paris-Sud, UVSQ, Institut Gustave Roussy, Villejuif, France; Cancer Epidemiology Centre, Cancer Council Victoria and Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourn, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Inserm, Centre de Recherche en Epidémiologie et Santé des Populations (CESP, U1018), Université Paris-Saclay, Université Paris-Sud, UVSQ, Institut Gustave Roussy, Villejuif, France; Cancer Epidemiology Centre, Cancer Council Victoria and Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourn</wicri:regionArea><wicri:noRegion>University of Melbourn</wicri:noRegion></affiliation></author><author><name sortKey="Clavel Chapelon, Francoise" sort="Clavel Chapelon, Francoise" uniqKey="Clavel Chapelon F" first="Françoise" last="Clavel-Chapelon">Françoise Clavel-Chapelon</name><affiliation wicri:level="1"><nlm:affiliation>Inserm, Centre de Recherche en Epidémiologie et Santé des Populations (CESP, U1018), Université Paris-Saclay, Université Paris-Sud, UVSQ, Institut Gustave Roussy, Villejuif, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Inserm, Centre de Recherche en Epidémiologie et Santé des Populations (CESP, U1018), Université Paris-Saclay, Université Paris-Sud, UVSQ, Institut Gustave Roussy, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Kaaks, Rudolf" sort="Kaaks, Rudolf" uniqKey="Kaaks R" first="Rudolf" last="Kaaks">Rudolf Kaaks</name><affiliation wicri:level="3"><nlm:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Barrdahl, Myrto" sort="Barrdahl, Myrto" uniqKey="Barrdahl M" first="Myrto" last="Barrdahl">Myrto Barrdahl</name><affiliation wicri:level="3"><nlm:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Boeing, Heiner" sort="Boeing, Heiner" uniqKey="Boeing H" first="Heiner" last="Boeing">Heiner Boeing</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal</wicri:regionArea><wicri:noRegion>Nuthetal</wicri:noRegion><wicri:noRegion>Nuthetal</wicri:noRegion><wicri:noRegion>Nuthetal</wicri:noRegion></affiliation></author><author><name sortKey="Trichopoulou, Antonia" sort="Trichopoulou, Antonia" uniqKey="Trichopoulou A" first="Antonia" last="Trichopoulou">Antonia Trichopoulou</name><affiliation wicri:level="3"><nlm:affiliation>Hellenic Health Foundation, Athens, Greece; WHO Collaborating Center for Nutrition and Health, Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Athens, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Hellenic Health Foundation, Athens, Greece; WHO Collaborating Center for Nutrition and Health, Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Athens</wicri:regionArea><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Lagiou, Pagona" sort="Lagiou, Pagona" uniqKey="Lagiou P" first="Pagona" last="Lagiou">Pagona Lagiou</name><affiliation wicri:level="3"><nlm:affiliation>Hellenic Health Foundation, Athens, Greece; WHO Collaborating Center for Nutrition and Health, Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Athens, Greece; Department of Epidemiology, Harvard School of Public Health, Boston, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Hellenic Health Foundation, Athens, Greece; WHO Collaborating Center for Nutrition and Health, Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Athens, Greece; Department of Epidemiology, Harvard School of Public Health, Boston</wicri:regionArea><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Naska, Androniki" sort="Naska, Androniki" uniqKey="Naska A" first="Androniki" last="Naska">Androniki Naska</name><affiliation wicri:level="3"><nlm:affiliation>Hellenic Health Foundation, Athens, Greece; WHO Collaborating Center for Nutrition and Health, Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Athens, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Hellenic Health Foundation, Athens, Greece; WHO Collaborating Center for Nutrition and Health, Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Athens</wicri:regionArea><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Masala, Giovanna" sort="Masala, Giovanna" uniqKey="Masala G" first="Giovanna" last="Masala">Giovanna Masala</name><affiliation wicri:level="1"><nlm:affiliation>Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute - ISPO, Florence, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute - ISPO, Florence</wicri:regionArea><wicri:noRegion>Florence</wicri:noRegion></affiliation></author><author><name sortKey="Agnoli, Claudia" sort="Agnoli, Claudia" uniqKey="Agnoli C" first="Claudia" last="Agnoli">Claudia Agnoli</name><affiliation wicri:level="1"><nlm:affiliation>Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milano, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milano</wicri:regionArea><wicri:noRegion>Milano</wicri:noRegion></affiliation></author><author><name sortKey="Polidoro, Silvia" sort="Polidoro, Silvia" uniqKey="Polidoro S" first="Silvia" last="Polidoro">Silvia Polidoro</name><affiliation wicri:level="3"><nlm:affiliation>Human Genetics Foundation (HuGeF), Torino, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Human Genetics Foundation (HuGeF), Torino</wicri:regionArea><placeName><settlement type="city">Turin</settlement><region type="région" nuts="2">Piémont</region></placeName></affiliation></author><author><name sortKey="Tumino, Rosario" sort="Tumino, Rosario" uniqKey="Tumino R" first="Rosario" last="Tumino">Rosario Tumino</name><affiliation wicri:level="1"><nlm:affiliation>Cancer Registry and Histopathology Unit, "Civic M.P. Arezzo" Hospital, ASP Ragusa, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Cancer Registry and Histopathology Unit, "Civic M.P. Arezzo" Hospital, ASP Ragusa</wicri:regionArea><wicri:noRegion>ASP Ragusa</wicri:noRegion></affiliation></author><author><name sortKey="Panico, Salvatore" sort="Panico, Salvatore" uniqKey="Panico S" first="Salvatore" last="Panico">Salvatore Panico</name><affiliation wicri:level="1"><nlm:affiliation>Dipartimento di Medicina Clinica e Chirurgia, Federico II University, Naples, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Medicina Clinica e Chirurgia, Federico II University, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Dolle, Martijn" sort="Dolle, Martijn" uniqKey="Dolle M" first="Martijn" last="Dollé">Martijn Dollé</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven</wicri:regionArea><wicri:noRegion>Bilthoven</wicri:noRegion></affiliation></author><author><name sortKey="Peeters, Petra H M" sort="Peeters, Petra H M" uniqKey="Peeters P" first="Petra H M" last="Peeters">Petra H M. Peeters</name><affiliation wicri:level="3"><nlm:affiliation>Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands; MRC-PHE Centre for Environment and Health, Dept of Epidemiology and Biostatistics, School of Public Health, Imperial College, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands; MRC-PHE Centre for Environment and Health, Dept of Epidemiology and Biostatistics, School of Public Health, Imperial College, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Onland Moret, N Charlotte" sort="Onland Moret, N Charlotte" uniqKey="Onland Moret N" first="N Charlotte" last="Onland-Moret">N Charlotte Onland-Moret</name><affiliation wicri:level="3"><nlm:affiliation>Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Sandanger, Torkjel M" sort="Sandanger, Torkjel M" uniqKey="Sandanger T" first="Torkjel M" last="Sandanger">Torkjel M. Sandanger</name><affiliation wicri:level="1"><nlm:affiliation>Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø</wicri:regionArea><wicri:noRegion>Tromsø</wicri:noRegion></affiliation></author><author><name sortKey="N St, Therese H" sort="N St, Therese H" uniqKey="N St T" first="Therese H" last="N St">Therese H. N St</name><affiliation wicri:level="1"><nlm:affiliation>Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø</wicri:regionArea><wicri:noRegion>Tromsø</wicri:noRegion></affiliation></author><author><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name><affiliation wicri:level="1"><nlm:affiliation>Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway; Department of Research, Cancer Registry of Norway, Institute of Population-Based Cancer Research, Oslo, Norway; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Genetic Epidemiology Group, Folkhälsan Research Center, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway; Department of Research, Cancer Registry of Norway, Institute of Population-Based Cancer Research, Oslo, Norway; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Genetic Epidemiology Group, Folkhälsan Research Center, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Quir S, J Ram N" sort="Quir S, J Ram N" uniqKey="Quir S J" first="J Ram N" last="Quir S">J Ram N Quir S</name><affiliation wicri:level="1"><nlm:affiliation>Public Health Directorate, Asturias, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Public Health Directorate, Asturias</wicri:regionArea><wicri:noRegion>Asturias</wicri:noRegion></affiliation></author><author><name sortKey="Agudo, Antonio" sort="Agudo, Antonio" uniqKey="Agudo A" first="Antonio" last="Agudo">Antonio Agudo</name><affiliation wicri:level="3"><nlm:affiliation>Unit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology-IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Unit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology-IDIBELL, L'Hospitalet de Llobregat, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Rodriguez Barranco, Miguel" sort="Rodriguez Barranco, Miguel" uniqKey="Rodriguez Barranco M" first="Miguel" last="Rodriguez-Barranco">Miguel Rodriguez-Barranco</name><affiliation wicri:level="1"><nlm:affiliation>Escuela Andaluza de Salud Pública, Instituto de Investigación Biosanitaria ibsn Granada, Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain; CIBER de Epidemiología y Salud Pública (CIBERESP), Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Escuela Andaluza de Salud Pública, Instituto de Investigación Biosanitaria ibsn Granada, Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain; CIBER de Epidemiología y Salud Pública (CIBERESP)</wicri:regionArea><wicri:noRegion>Spain; CIBER de Epidemiología y Salud Pública (CIBERESP)</wicri:noRegion></affiliation></author><author><name sortKey="Huerta Casta O, Jose Maria" sort="Huerta Casta O, Jose Maria" uniqKey="Huerta Casta O J" first="José María" last="Huerta Casta O">José María Huerta Casta O</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Murcia Regional Health Council, IMIB-Arrixaca, Murcia, Spain; CIBER de Epidemiología y Salud Pública (CIBERESP), Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Epidemiology, Murcia Regional Health Council, IMIB-Arrixaca, Murcia, Spain; CIBER de Epidemiología y Salud Pública (CIBERESP)</wicri:regionArea><wicri:noRegion>Spain; CIBER de Epidemiología y Salud Pública (CIBERESP)</wicri:noRegion></affiliation></author><author><name sortKey="Barricarte, Aurelio" sort="Barricarte, Aurelio" uniqKey="Barricarte A" first="Aurelio" last="Barricarte">Aurelio Barricarte</name><affiliation wicri:level="1"><nlm:affiliation>Navarra Public Health Institute, Pamplona, Spain; Navarra Institute for Health Research (IdiSNA) Pamplona, Spain; CIBER de Epidemiología y Salud Pública (CIBERESP), Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Navarra Public Health Institute, Pamplona, Spain; Navarra Institute for Health Research (IdiSNA) Pamplona, Spain; CIBER de Epidemiología y Salud Pública (CIBERESP)</wicri:regionArea><wicri:noRegion>Spain; CIBER de Epidemiología y Salud Pública (CIBERESP)</wicri:noRegion></affiliation></author><author><name sortKey="Fernandez, Ander Matheu" sort="Fernandez, Ander Matheu" uniqKey="Fernandez A" first="Ander Matheu" last="Fernández">Ander Matheu Fernández</name><affiliation wicri:level="1"><nlm:affiliation>Cellular Oncology Group, Biodonostia Health Research Institute, Paseo Dr. Beguiristain s/n, San Sebastian, Spain; IKERBASQUE, Basque Foundation, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Cellular Oncology Group, Biodonostia Health Research Institute, Paseo Dr. Beguiristain s/n, San Sebastian, Spain; IKERBASQUE, Basque Foundation</wicri:regionArea><wicri:noRegion>Basque Foundation</wicri:noRegion></affiliation></author><author><name sortKey="Travis, Ruth C" sort="Travis, Ruth C" uniqKey="Travis R" first="Ruth C" last="Travis">Ruth C. Travis</name><affiliation wicri:level="4"><nlm:affiliation>Cancer Epidemiology Unit, Nuffield Department of Population Health University of Oxford, Oxford UK.</nlm:affiliation><orgName type="university">Université d'Oxford</orgName><country>Royaume-Uni</country><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Vineis, Paolo" sort="Vineis, Paolo" uniqKey="Vineis P" first="Paolo" last="Vineis">Paolo Vineis</name><affiliation wicri:level="3"><nlm:affiliation>School of Public Health, Imperial College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Public Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Muller, David C" sort="Muller, David C" uniqKey="Muller D" first="David C" last="Muller">David C. Muller</name><affiliation wicri:level="3"><nlm:affiliation>School of Public Health, Imperial College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Public Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name><affiliation wicri:level="3"><nlm:affiliation>School of Public Health, Imperial College London, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Public Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Gunter, Marc" sort="Gunter, Marc" uniqKey="Gunter M" first="Marc" last="Gunter">Marc Gunter</name><affiliation wicri:level="3"><nlm:affiliation>International Agency for Research on Cancer (IARC), Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer (IARC), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Romieu, Isabelle" sort="Romieu, Isabelle" uniqKey="Romieu I" first="Isabelle" last="Romieu">Isabelle Romieu</name><affiliation wicri:level="3"><nlm:affiliation>International Agency for Research on Cancer (IARC), Lyon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer (IARC), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Herceg, Zdenko" sort="Herceg, Zdenko" uniqKey="Herceg Z" first="Zdenko" last="Herceg">Zdenko Herceg</name><affiliation wicri:level="3"><nlm:affiliation>International Agency for Research on Cancer (IARC), Lyon, France. Electronic address: herceg@iarc.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer (IARC), Lyon</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author></analytic><series><title level="j">European journal of cancer (Oxford, England : 1990)</title><idno type="eISSN">1879-0852</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Age Factors</term><term>Aged</term><term>Breast Neoplasms (genetics)</term><term>Case-Control Studies</term><term>DNA Methylation (genetics)</term><term>DNA Methylation (physiology)</term><term>Epigenesis, Genetic (genetics)</term><term>Epigenomics</term><term>Female</term><term>Genetic Predisposition to Disease (genetics)</term><term>Humans</term><term>Middle Aged</term><term>Postmenopause (genetics)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Facteurs de l'âge</term><term>Femelle</term><term>Humains</term><term>Méthylation de l'ADN (génétique)</term><term>Méthylation de l'ADN (physiologie)</term><term>Post-ménopause (génétique)</term><term>Prédisposition génétique à une maladie (génétique)</term><term>Sujet âgé</term><term>Tumeurs du sein (génétique)</term><term>Épigenèse génétique (génétique)</term><term>Épigénomique</term><term>Études cas-témoins</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Breast Neoplasms</term><term>DNA Methylation</term><term>Epigenesis, Genetic</term><term>Genetic Predisposition to Disease</term><term>Postmenopause</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Méthylation de l'ADN</term><term>Post-ménopause</term><term>Prédisposition génétique à une maladie</term><term>Tumeurs du sein</term><term>Épigenèse génétique</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Méthylation de l'ADN</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>DNA Methylation</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Age Factors</term><term>Aged</term><term>Case-Control Studies</term><term>Epigenomics</term><term>Female</term><term>Humans</term><term>Middle Aged</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Facteurs de l'âge</term><term>Femelle</term><term>Humains</term><term>Sujet âgé</term><term>Épigénomique</term><term>Études cas-témoins</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A vast majority of human malignancies are associated with ageing, and age is a strong predictor of cancer risk. Recently, DNA methylation-based marker of ageing, known as 'epigenetic clock', has been linked with cancer risk factors. This study aimed to evaluate whether the epigenetic clock is associated with breast cancer risk susceptibility and to identify potential epigenetics-based biomarkers for risk stratification.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Danemark</li><li>Espagne</li><li>Finlande</li><li>France</li><li>Grèce</li><li>Italie</li><li>Norvège</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Attique (région)</li><li>Auvergne-Rhône-Alpes</li><li>Bade-Wurtemberg</li><li>Californie</li><li>Catalogne</li><li>District de Karlsruhe</li><li>Grand Londres</li><li>Massachusetts</li><li>Oxfordshire</li><li>Piémont</li><li>Rhône-Alpes</li><li>Utrecht (province)</li></region><settlement><li>Athènes</li><li>Barcelone</li><li>Boston</li><li>Heidelberg</li><li>Londres</li><li>Lyon</li><li>Oxford</li><li>Turin</li><li>Utrecht</li></settlement><orgName><li>Université d'Oxford</li></orgName></list><tree><country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Ambatipudi, Srikant" sort="Ambatipudi, Srikant" uniqKey="Ambatipudi S" first="Srikant" last="Ambatipudi">Srikant Ambatipudi</name></region><name sortKey="Bouaoun, Liacine" sort="Bouaoun, Liacine" uniqKey="Bouaoun L" first="Liacine" last="Bouaoun">Liacine Bouaoun</name><name sortKey="Byrnes, Graham" sort="Byrnes, Graham" uniqKey="Byrnes G" first="Graham" last="Byrnes">Graham Byrnes</name><name sortKey="Chajes, Veronique" sort="Chajes, Veronique" uniqKey="Chajes V" first="Véronique" last="Chajes">Véronique Chajes</name><name sortKey="Clavel Chapelon, Francoise" sort="Clavel Chapelon, Francoise" uniqKey="Clavel Chapelon F" first="Françoise" last="Clavel-Chapelon">Françoise Clavel-Chapelon</name><name sortKey="Cuenin, Cyrille" sort="Cuenin, Cyrille" uniqKey="Cuenin C" first="Cyrille" last="Cuenin">Cyrille Cuenin</name><name sortKey="Durand, Geoffroy" sort="Durand, Geoffroy" uniqKey="Durand G" first="Geoffroy" last="Durand">Geoffroy Durand</name><name sortKey="Ferrari, Pietro" sort="Ferrari, Pietro" uniqKey="Ferrari P" first="Pietro" last="Ferrari">Pietro Ferrari</name><name sortKey="Gunter, Marc" sort="Gunter, Marc" uniqKey="Gunter M" first="Marc" last="Gunter">Marc Gunter</name><name sortKey="Herceg, Zdenko" sort="Herceg, Zdenko" uniqKey="Herceg Z" first="Zdenko" last="Herceg">Zdenko Herceg</name><name sortKey="Hernandez Vargas, Hector" sort="Hernandez Vargas, Hector" uniqKey="Hernandez Vargas H" first="Hector" last="Hernandez-Vargas">Hector Hernandez-Vargas</name><name sortKey="Le Calvez Kelm, Florence" sort="Le Calvez Kelm, Florence" uniqKey="Le Calvez Kelm F" first="Florence" last="Le Calvez-Kelm">Florence Le Calvez-Kelm</name><name sortKey="Perrier, Flavie" sort="Perrier, Flavie" uniqKey="Perrier F" first="Flavie" last="Perrier">Flavie Perrier</name><name sortKey="Romieu, Isabelle" sort="Romieu, Isabelle" uniqKey="Romieu I" first="Isabelle" last="Romieu">Isabelle Romieu</name><name sortKey="Sklias, Athena" sort="Sklias, Athena" uniqKey="Sklias A" first="Athena" last="Sklias">Athena Sklias</name></country><country name="États-Unis"><region name="Californie"><name sortKey="Horvath, Steve" sort="Horvath, Steve" uniqKey="Horvath S" first="Steve" last="Horvath">Steve Horvath</name></region><name sortKey="Lagiou, Pagona" sort="Lagiou, Pagona" uniqKey="Lagiou P" first="Pagona" last="Lagiou">Pagona Lagiou</name></country><country name="Danemark"><noRegion><name sortKey="Overvad, Kim" sort="Overvad, Kim" uniqKey="Overvad K" first="Kim" last="Overvad">Kim Overvad</name></noRegion></country><country name="Australie"><noRegion><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name></noRegion><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name></country><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Kaaks, Rudolf" sort="Kaaks, Rudolf" uniqKey="Kaaks R" first="Rudolf" last="Kaaks">Rudolf Kaaks</name></region><name sortKey="Barrdahl, Myrto" sort="Barrdahl, Myrto" uniqKey="Barrdahl M" first="Myrto" last="Barrdahl">Myrto Barrdahl</name><name sortKey="Boeing, Heiner" sort="Boeing, Heiner" uniqKey="Boeing H" first="Heiner" last="Boeing">Heiner Boeing</name></country><country name="Grèce"><region name="Attique (région)"><name sortKey="Trichopoulou, Antonia" sort="Trichopoulou, Antonia" uniqKey="Trichopoulou A" first="Antonia" last="Trichopoulou">Antonia Trichopoulou</name></region><name sortKey="Naska, Androniki" sort="Naska, Androniki" uniqKey="Naska A" first="Androniki" last="Naska">Androniki Naska</name></country><country name="Italie"><noRegion><name sortKey="Masala, Giovanna" sort="Masala, Giovanna" uniqKey="Masala G" first="Giovanna" last="Masala">Giovanna Masala</name></noRegion><name sortKey="Agnoli, Claudia" sort="Agnoli, Claudia" uniqKey="Agnoli C" first="Claudia" last="Agnoli">Claudia Agnoli</name><name sortKey="Panico, Salvatore" sort="Panico, Salvatore" uniqKey="Panico S" first="Salvatore" last="Panico">Salvatore Panico</name><name sortKey="Polidoro, Silvia" sort="Polidoro, Silvia" uniqKey="Polidoro S" first="Silvia" last="Polidoro">Silvia Polidoro</name><name sortKey="Tumino, Rosario" sort="Tumino, Rosario" uniqKey="Tumino R" first="Rosario" last="Tumino">Rosario Tumino</name></country><country name="Pays-Bas"><noRegion><name sortKey="Dolle, Martijn" sort="Dolle, Martijn" uniqKey="Dolle M" first="Martijn" last="Dollé">Martijn Dollé</name></noRegion><name sortKey="Onland Moret, N Charlotte" sort="Onland Moret, N Charlotte" uniqKey="Onland Moret N" first="N Charlotte" last="Onland-Moret">N Charlotte Onland-Moret</name></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Peeters, Petra H M" sort="Peeters, Petra H M" uniqKey="Peeters P" first="Petra H M" last="Peeters">Petra H M. Peeters</name></region><name sortKey="Muller, David C" sort="Muller, David C" uniqKey="Muller D" first="David C" last="Muller">David C. Muller</name><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name><name sortKey="Travis, Ruth C" sort="Travis, Ruth C" uniqKey="Travis R" first="Ruth C" last="Travis">Ruth C. Travis</name><name sortKey="Vineis, Paolo" sort="Vineis, Paolo" uniqKey="Vineis P" first="Paolo" last="Vineis">Paolo Vineis</name></country><country name="Norvège"><noRegion><name sortKey="Sandanger, Torkjel M" sort="Sandanger, Torkjel M" uniqKey="Sandanger T" first="Torkjel M" last="Sandanger">Torkjel M. Sandanger</name></noRegion><name sortKey="N St, Therese H" sort="N St, Therese H" uniqKey="N St T" first="Therese H" last="N St">Therese H. N St</name></country><country name="Finlande"><noRegion><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name></noRegion></country><country name="Espagne"><noRegion><name sortKey="Quir S, J Ram N" sort="Quir S, J Ram N" uniqKey="Quir S J" first="J Ram N" last="Quir S">J Ram N Quir S</name></noRegion><name sortKey="Agudo, Antonio" sort="Agudo, Antonio" uniqKey="Agudo A" first="Antonio" last="Agudo">Antonio Agudo</name><name sortKey="Barricarte, Aurelio" sort="Barricarte, Aurelio" uniqKey="Barricarte A" first="Aurelio" last="Barricarte">Aurelio Barricarte</name><name sortKey="Fernandez, Ander Matheu" sort="Fernandez, Ander Matheu" uniqKey="Fernandez A" first="Ander Matheu" last="Fernández">Ander Matheu Fernández</name><name sortKey="Huerta Casta O, Jose Maria" sort="Huerta Casta O, Jose Maria" uniqKey="Huerta Casta O J" first="José María" last="Huerta Casta O">José María Huerta Casta O</name><name sortKey="Rodriguez Barranco, Miguel" sort="Rodriguez Barranco, Miguel" uniqKey="Rodriguez Barranco M" first="Miguel" last="Rodriguez-Barranco">Miguel Rodriguez-Barranco</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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|texte= DNA methylome analysis identifies accelerated epigenetic ageing associated with postmenopausal breast cancer susceptibility.
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